Cream Royal Albert Hall A guitar pickup is actually just like a powerful microphone coil. For decades, powerful microphones have been wired with the style coil attached to the primary of the microphone's transformer, and maybe not referenced to ground (‘floating'). The microphone's situation is typically connected to the cable shield, that will be attached to the microphone amplifier's ground (see Rane's site for more discussion).
By and big, dynamic microphones are very quiet devices consequently of the combination of transformer isolation and healthy, hanging sign lines during, in addition to protected, humbucking coils.
Therefore why don't you guitars? Guitars are once plagued by noise. Humbucking pickups are only a partial (though essential!) solution. Well-known answer is always to move your guitar collection to a healthy output, as being a microphone. A similar idea was published that 2001 patent software like this Cream Royal Albert Hall?